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Lithium orotate is just very low-dose lithium. It has surprisingly low solubility. (Most lithium salts are either deliquescent, or totally insoluble.) Lithium increases mellowness and patience, while reducing grumpiness. However, titrating the correct dose (best approached from below) is important. Excessive urination and thirst are the first symptoms of overdose. Worse, as well as goiter, are possible.

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